Understanding the Functioning of Semaglutide and Tirzepatide Semaglutide for Weight Loss Semaglutide, originally developed for managing Type 2 Diabetes, is now often prescribed (under the brand name Wegovy) for weight loss due to its effectiveness in reducing appetite and enhancing satiety
With a 0.3 mL insulin syringe that has 0.5-unit graduations, you can reliably measure down to about 1-2 units
The theoretical argument is that it might reduce the acute receptor burden that triggers GI side effects, since each injection delivers less peptide
The most practical ceiling for self-directed use is conservative: start near 1,000 mg/day, judge tolerance, and avoid assuming higher doses create better results
The standard recommendations apply: abdomen, upper thigh, or upper arm, rotating sites to prevent lipodystrophy