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Natalizumab carries a risk of progressive multifocal leukoencephalopathy (PML) and requires enrollment in a restricted distribution program

Drugs like these mimic the action of a natural hormone, glucagon-like peptide-1 (GLP-1), crucial in regulating blood sugar levels

You should contact your GP if you experience: Progressive memory loss that interferes with daily activities, such as forgetting important appointments, repeatedly asking the same questions, or getting lost in familiar places Sudden onset of confusion or disorientation, particularly if accompanied by other neurological symptoms such as severe headache, visual changes, weakness, or speech difficulties Significant mood changes , including depression, anxiety, or personality alterations, which can sometimes affect cognitive function Memory problems alongside other concerning symptoms , such as unexplained weight loss (beyond expected therapeutic effect), persistent fatigue, or changes in sleep patterns Seek urgent medical attention by calling 999 if you experience: Sudden confusion with facial drooping, arm weakness, or speech problems (FAST symptoms of stroke) Severe, sudden confusion with focal neurological symptoms If you have diabetes and experience confusion, check your blood glucose level as hypoglycaemia can cause cognitive symptoms, especially if you take GLP-1 medications with insulin or sulfonylureas

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