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Inflammation and peripheral nerve injury increase NGF expression and sensitise peripheral nociceptive terminals through the induction of gene expression in nociceptors [28]

Important: For research use only

345 The RNA sensor TLR7 undertakes the challenging role of efficiently recognizing and responding to foreign genomic material while maintaining tolerance towards self-derived nucleic acids

The integration of ferroptosis-targeted approaches within the comprehensive therapeutic paradigms has the potential to revolutionize the management of RM by addressing this complex condition with a mechanistic and tailored approach