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PE = Pulmonary Embolus
The clinical data suggesting a possible association come from post-marketing surveillance data that have substantial risk for bias and do not control for important confounding variables
CJC-1295 mimics that signal, but with a dramatically extended duration of action compared to the natural hormone
It is studied as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme linked to metabolic and oncogenic pathways in research models
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