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Due to our sample size, study design, and number of clinically relevant matching variables, we opted for a simple, unadjusted analysis to inform a conclusion as to whether the technique is sufficiently safe to proceed to phase two trials to test efficacy
The complex was subjected to size-exclusion chromatography (SEC) on a Superose 6 Increase 10/300 column (GE Healthcare) equilibrated with 20 mM HEPES pH 7.5, 100 mM NaCl, 2 mM MgCl 2 , 1 M semaglutide, 0.01% (w/v) LMNG, and 0.006% (w/v) CHS