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Higher doses often yield stronger efficacy but also greater gastrointestinal issues, tolerability drop-outs, etc
PMID: 40098249
13(4): 692 Di Cesare Mannelli L, Ghelardini C, Toscano A, Pacini A, Bartolini A (2010) The neuropathy-protective agent acetyl-l-carnitine activates protein kinase C- and MAPKs in a rat model of neuropathic pain
The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase
The former work by exerting high GST-inhibitory activity, while the latter comprise inactive compounds designed to target tumor tissue locally by undergoing GST catalysis in the tumor to release cytotoxic metabolites
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