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Blachier F, Boutry C, Bos C, Tom D
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Studies show compounded and brand-name GLP-1 agents produce comparable weight-loss outcomes when dosed equivalently
The FDA removed tirzepatide from the drug shortage list in December 2024 and semaglutide in February 2025, eliminating the primary legal basis for "essentially a copy" compounding of these substances
Cells were then loaded for 30 min with 2 mol/l Fluo-4AM (cell-permeant formulation, Thermofisher) in Lockes buffer consisted of 154 mmol/l NaCl, 4 mmol/l NaHCO 3 , 5 mmol/l KCl, 2,3 mmol/l CaCl 2 , 1 mmol/l MgCl 2 , 5 mmol/l glucose, 10 mmol/l Hepes
