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Asia Pacific 5.4.1.4
These results indicate that many mutations acquired during early rounds of PANCE and dual selection were not essential for gasdermin D cleavage and, in some cases, were detrimental to protease efficiency in the context of GD_L variants
Tumor size, survival time of mice, GPX4 protein levels, 4-HNE levels, and Ki67 expression were measured (Fig
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