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The therapeutic effect of GLP-1 on MASH is thought to be due to a reduction in body weight caused by a decrease in appetite and insulin resistance, which leads to an improvement in dyslipidemia and hepatic inflammation 33,34
Personal or family history of medullary thyroid carcinoma or MEN2 is an important label-based caution
Ipamorelin acts as a ghrelin receptor agonist with selective growth hormone secretion, while tesamorelin is a growth hormone-releasing hormone (GHRH) analog approved for specific lipodystrophy indications
Curr Med Res Opin 2008;24:275286
nevertheless, this did not influence overall exposure
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