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Eligibility criteria Inclusion criteria were summarized according to the PICOS principle: (1) P (Participants): No restriction on diseases

2000mg l-carnitine per day provides the maximum effect in adults

It is investigated for its activity at central melanocortin receptors, particularly MC3R and MC4R, which are involved in neuroendocrine signaling

This deficiency is often triggered by heavy exercise, and can also manifest as a result of exposure to cold, infection, emotional distress, and/or fasting [132]

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