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MSA-DH dependent formation of D-malate was indicated at a retention time of 18.4 min (yellow line)
In previous GLP-1- or exendin-P5-bound active structures 3,4 , the ECD shows a fully extended open conformation, whereas in the peptide 5-bound active-like structure 12 , the ECD is less extended since it makes fewer interactions with the truncated peptide 5
A certificate of analysis verifies a compounds identity against a known reference standard, and there is no approved reference standard for a drug no regulator has cleared
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Mentias, A
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