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A representative dynamic model utilizing ordinary differential equations, which captures the response of Nrf2, Keap1, Srxn1, and GSH under oxidative stress, was proposed by Hiemstra et al

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Results Senescence-associated markers were enhanced in keloid fibroblasts and lesions Analysis of the heterogeneity of keloid cells revealed 28 cellular clusters (027) using unsupervised clustering of 34,043 cells based on established lineage-specific marker genes (Supplementary Fig