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But is GLP-1 safe for long-term use

Damar, U., Gersner, R., Johnstone, J

Endocrine Practice, Volume 30, Issue 5, S70

However, oral semaglutide (Rybelsus) must be taken on an empty stomach, at least 30 minutes before a meal

As a GLP-1 receptor agonist, semaglutide mimics the action of the naturally occurring incretin hormone GLP-1, which is released from the intestine in response to food intake