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The combination of phentermine with semaglutide raises separate timing questions, as phentermine is a stimulant best taken in the morning to avoid insomnia
Because oral bioavailability of semaglutide is low (~1%), Rybelsus requires strict dosing conditions empty stomach, no more than 4 oz (120 mL) of plain water, at least 30 minutes before the first food or drink of the day
47, Nov
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