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The primary evidence comes from the 2017 Cell paper using aged and chemotherapy-treated mice, and subsequent mechanistic studies
Using the Broad Institute's Connectivity Map (CMap), which compares gene expression signatures across thousands of compounds, Pickart et al
This is a firm rule, not a gray area
Stress reduction practices like diaphragmatic breathing, yoga, meditation, and journaling can be incredibly effective for reducing stress levels in the body
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