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This inherent limitation of oral oligomeric DOCA-G1As highlights the importance of focusing on prevention, rather than treatment, of severe diabetes through oral GLP-1A administration

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The injectable form delivers semaglutide directly into subcutaneous tissue, where it absorbs slowly and maintains steady blood levels for seven days

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Fountoulakis et al., 2025) as well as antioxidant therapeutic approaches (Mynarska et al., 2024