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It is also unusually stable in gastric acid, which is why oral dosing is even theoretically plausible
Interestingly, the presentation of DAPT and BMS appeared to exert the opposite action to TB-500, suggesting that the Notch/NF-B pathways may mediate TB-500s proposed action on angiogenesis
Langan RC, Goodbred AJ
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The lack of FDA approval for human use and the need for higher doses in some experimental settings underscore the importance of evaluating safety and efficacy under strict medical supervision
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