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The water itself doesn't "go bad" in a dramatic way, but you can no longer rely on the manufacturer-validated preservative activity
However, like any other treatment, its not without potential side effects
Generally, oral glutathione can take up to 4 to 8 weeks to start showing results
Notably, despite being a large polyphenol, curcumin is lipophilic and can cross the bloodbrain barrier at sufficient concentrations to exert effects in the CNS (79)
Mainly, it helps in the cleansing process, which overall refreshes the skin
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