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Whereas peripheral factors from the gastrointestinal system are known to exert influence on homeostatic feeding areas, such as the brainstemhypothalamic circuit, there is evidence that they can alsodirectly or indirectlyinfluence the brains reward system (Klockars et al., 2021
Yakar S, Setser J, Zhao H, Stannard B, Haluzik M, Glatt V, Bouxsein ML, Kopchick JJ, LeRoith D
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National Institutes of Health.
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