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This is based on the observation that the livers of GCLM KO mice in all diet groups have high levels of active (phosphorylated) LKB1, a redox-sensitive kinase and the primary hepatic AMPK kinase 24

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Inhibitors of cyclin-dependent kinase 4 (CDK4), a serine-/threonine kinase controlling cell survival and death, reduce stress-induced eryptosis [158]

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Drug Metab Dispos