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You have your medication, you have your plan, and now you face the practical question: when exactly should you hit the start button

The 2022 NEJM study, which showed sustained and significant weight loss with tirzepatide, primarily focused on people with obesity, not excess weight (pre-obesity)

Smaller, frequent meals may help if you experience discomfort from eating larger portions

talk to your doctor about anti-nausea medications if needed Will it get better