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At the end of the trial, patients taking tirzepatide experienced 36 per hour, a reduction of nearly 30%
This central form of IR involves alterations in similar pathways but manifests distinctively in reduced synaptic plasticity and neurotransmitter regulation, impacting mood and cognitive functions [6]
Withdrawal symptoms can also occur when individuals stop taking GLP-1 medications: Reduced side effects: While semaglutide or tirzepatide can lead to side effects like acid reflux, nausea, constipation and abdominal pain, stopping the medication can reduce these side effects
Seek urgent or same-day medical attention if you experience: Severe, persistent upper abdominal pain, with or without vomiting this may indicate pancreatitis, a recognised class warning with GLP-1-based therapies
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