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When peptides are exposed to temperatures above their recommended storage range, the amino acid chains begin to unfold
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McGowan said most patients in his practice stay on the 10 mg or 15 mg doses of Zepbound, although that often depends on supply
Mounjaro and Zepbound have not been studied in patients with severe gastrointestinal disease, including severe gastroparesis, and are therefore not recommended in these patients. Lilly additionally warned against the use of these products for individuals under the age of 18 years, citing that while clinical trials are ongoing, the safety and efficacy of tirzepatide have not been established in younger patients
