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Similarly, people with a history of psychiatric medications were 12% more likely to discontinue treatment within the first year, while those living with cardiovascular disease or other chronic conditions were around 10% more likely to stop treatment early, also suggesting a higher likelihood of experiencing adverse effects

In studies , some people whose blood sugars were controlled on semaglutide saw their prediabetes or diabetes get worse after stopping semaglutide

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As weight decreases, the body often fights back by increasing appetite hormones and lowering energy use