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It is derived from the HGH amino acid sequence 176191 and was designed to retain the hormones fat-metabolising properties while avoiding its growth-promoting and blood sugaraltering effects (1)
SURMOUNT-1: la referencia en obesidad sin diabetes SURMOUNT-1 (Jastreboff et al., NEJM 2022) incluy 2.539 participantes con obesidad (IMC medio 38 kg/m) o sobrepeso con al menos una complicacin relacionada con el peso, sin diabetes tipo 2
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NICE guidance (NG28) recommends individualised HbA1c targets, typically around 48 mmol/mol (6.5%) for most adults with type 2 diabetes, or up to 53 mmol/mol (7.0%) for those at risk of hypoglycaemia or with other individual factors
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