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Assesses the acid/base balance to ensure minimal irritation upon injection and confirm the solution is within the correct range for subcutaneous administration

10.1016/j.joca.2015.07.008 Osteoarthritis Cartil

TB-500 is most commonly administered subcutaneously or intraperitoneally in animal wound models, though topical formulations have also demonstrated activity in corneal and cutaneous wound models

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At low concentrations, it increases MMP1 and MMP2, which break down damaged or disorganized collagen and elastin