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Ipamorelin is a 3rd generation GHRP and is regarded as the cleanest of the GHRP's

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In the SURMOUNT-1 clinical trial, which enrolled 2,539 adults with obesity or overweight (without diabetes), participants on the highest weekly dose of tirzepatide (15 mg) achieved an average weight loss of 20.9% of their body weight (approximately 52 pounds) over 72 weeks