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The construct and various mutants of human GIPR were cloned into pcDNA3.1 vector for cAMP accumulation and whole-cell binding assays
In the SURMOUNT-OSA trial, tirzepatide reduced the apnea-hypopnea index by up to 62.8%, translating to approximately 30 fewer breathing interruptions per hour of sleep
Provide complete entries for each therapy: drug name, start date, end date (or leave blank if ongoing), outcome, and whether it will be continued
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