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SGLT2 Inhibitors The 2025 JCS/JHFS and 2023 ESC guidelines recommend SGLT2 inhibitors for HFpEF with a Class Ia compared with the 2022 ACC/AHA/HFSA guidelines that still assign a Class IIa recommendation

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of antiphospholipid antibodies and a hypercoagulable state

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Though side effects are possible, these results suggest semaglutide could become the first approved drug to treat this growing global health concern