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Four weeks is a reasonable window for something acute and eight for something that has been there a while

High levels of the transcription factor NRF2 can induce metabolic reprogramming in dormant tumor cells, re-establishing redox homeostasis and de novo synthesis of nucleotides, accelerating the activation of tumor cells and tumor recurrence

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This compound also induces the expression of thymic stromal lymphopoietin (TSLP) which participates in the induction of an AD-like phenotype (227)

233,234 In this process, toll-like receptors (TLRs) and NF-B play important roles