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Pyrroloquinoline Quinone (PQQ): A potent antioxidant compound that supports mitochondrial health, brain function, and cellular energy production while helping reduce oxidative stress

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GLP-1 receptor agonists bind to GLP-1 receptors on pancreatic beta cells, stimulating glucose-dependent insulin secretion while suppressing inappropriate glucagon release

The combination of metformin and semaglutide represents a scientifically grounded approach to addressing both insulin resistance and appetite regulation

The mechanism of action involves several complementary pathways: Enhanced insulin secretion : GLP-1 agonists stimulate glucose-dependent insulin release from pancreatic beta cells, meaning insulin is only released when blood glucose levels are elevated, thereby reducing the risk of hypoglycaemia