At least not in mice
So far, clinical trials have not demonstrated a consistent rise in atrial fibrillation events related to this modest chronotropic change
What responsible prescribing looks likeand why it matters Its essential for physicians to responsibly prescribe drugs in every field of medicine to make sure theyre doing more benefit than harm while minimizing disease
On February 6, however, FDAs approach appeared to shift with an announcement that it would be taking steps both to restrict GLP-1 active pharmaceutical ingredients (APIs) that continue to be used in non-FDA-approved compounded products to combat misleading direct-to-consumer advertising and marketing. Unequivocally, FDA warned: Entities engaged in the manufacture, distribution, or marketing of unapproved compounded GLP-1 products should be aware that failure to adequately address any violations may result in legal action without further notice, including, without limitation, seizure and injunction. FDA specifically named Hims & Hers a popular and outspoken telehealth provider that advertises compounded GLP-1 products in the announcement
the HFD group mainly concentrated on metabolites like betaine, phenylalanine, and taurine