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This underscores why simply not eating, which is effectively what some people do when they first start retatrutide and let side effects dictate their nutrition, is the worst possible approach
Results vary depending on what you're dealing with, but the feedback we hear most often is that people feel "like a new person" within an hour or two of their session
J Diabetes Res Clin Metab
Source: Eli Lilly press release, May 21, 2026
Butsch et al
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