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Publication bias and poor recording of adverse events, which is common in clinical trials, may however explain such paucity of safety signals
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Analysis of publicly available datasets for mtRNR1 (MOTS-c) mRNA levels in pancreatic islet cells or EndoC-HB1 cells treated with inflammatory cytokines showed that MOTS-c levels decrease under T1D conditions (Fig
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In 2017, a small single-center randomized trial of 62 participants, but with longer follow-up, found benefit with exenatide given once weekly (see graph below)
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