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The authors of this study did note potential negative mood changes associated with semaglutide in patients with Type 2 diabetes and a history of depression. In September 2024, a research team from the Perelman School of Medicine at the University of Pennsylvania determined that semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or suicidal behavior in persons without known major mental health disorders. Though questions remain about Ozempics ability to cause depression, these studies suggest that the drug may exacerbate symptoms in patients who have already been living with certain mental health concerns
Mounjaro Approved by the FDA for Type 2 Diabetes , Mounjaro helps lower blood sugar levels while supporting weight loss as a secondary benefit
Zhang Y, Zhang C, Shu J, et al
It can be weakened by things like stress, illness, a poor diet, insufficient sleep or lack of activity
Yan Y, Liu B, Du J et al (2021) SGLT2i versus ARNI in heart failure with reduced ejection fraction: a systematic review and meta-analysis
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