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Published work on intranasal peptide delivery (for insulin analogs, calcitonin, and oxytocin) demonstrates that bioavailability for this size class without enhancers is typically in the low single-digit percent range, though these data are from different peptides with different charge profiles
[63] Pernicious anemia can be treated with intramuscular injections of vitamin B 12
Other Uses: Support in metabolic syndrome, prediabetes, cognitive aging
Even though B12 shots are appropriate for use in those who are low or deficient in this vitamin, theres no evidence that B12 shots offer any benefits for people with optimal B12 levels.
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Is there clinical evidence that this can help
