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However, if you have cancer, glutathione may accelerate cancer growth, aid in metastasis, and prevent chemotherapy from working

Higher amounts of mitochondrial mammalian Trx-2, have been correlated with protection against t -butylhydroperoxide and etoposide-induced apoptosis (Chen et al., 2002) and cells deficient in Trx-2 had increased ROS production and exacerbated apoptosis (Tanaka et al., 2002)

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DOI:10.1111/ijd.12999 [ Links ] 27

However, GSH is found in intracellular organelles including endoplasmic reticulum (ER), nucleus, and mitochondria to control compartment-specific needs and functions (Mari et al., 2009, 2010)