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At 24 weeks, reductions in HbA1c levels were dose-related in the retatrutide groups ranging from 0.43 to 2.02%, versus 1.31% in the dulaglutide group and 0.01% in the placebo group [4]
A 2022 review of 76 clinical trials noted participants who used GLP-1s specifically for weight loss, took a higher dose, and/or used the medication for more than 26 weeks were at a higher risk for gallbladder issues
doi: 10.1517/17460441.2014.942638 67 HorowitzMRaynerCKJonesKL
References Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al
A: GLP-1s may be covered for approved indications (criteria vary by plan)
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