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For instance, a randomized controlled trial published in the "Journal of Clinical Endocrinology & Metabolism" found that individuals treated with GLP-1 receptor agonists experienced greater weight loss compared to the control group

Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides

These proposed complementary actions are expected to produce a more pronounced effect on weight loss than single or dual receptor agonists, though the precise contribution of each receptor pathway in humans continues to be studied