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Specificity is the key to increased productivity Unlike insulin, LONG R 3 IGF-I specifically targets and activates the type I IGF Receptor (IGF-IR) resulting in greater activation of downstream signaling cascades responsible for proliferation and inhibiting apoptosis
Eur J Intern Med 28:5258
Finner, A
In this model, knocking out either glp-1 or glp-4 function leads to failure of the germline to develop
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