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In that study, the glucose-sensing transcription factor carbohydrate response element binding protein (ChREBP) has been shown to initiate a regulatory program driving an early transcriptional activation of metabolic genes, which is followed by a second wave of transcriptional regulation wherein cell-cycle genes are activated and -cell identity genes are repressed
For many of the other spices, there arent even in vitro data, but rather only in silico , meaning just some kind of computer modeling that didnt actually test anything in a biological system
doi: 10.1111/jnc.15521 24 RodeAKOBuusTBMrazVAl-JaberiFAHLopezDVFordSLet al
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