Estos efectos son especialmente comunes durante las primeras semanas de tratamiento o cuando se aumenta la dosis, aunque en muchos pacientes este efecto sobre el vaciamiento gstrico puede atenuarse con el tiempo (taquifilaxia)
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However, liver mitochondria from mice lacking ANT1 and ANT2 can still undergo Ca 2 + -induced swelling and MPT, although at a higher threshold, which has been interpreted as evidence against a role for ANT in MPT (Kokoszka et al., 2004)
The relationship between collagen-boosting peptides and connective tissue repair also becomes relevant during this phase, as collagen forms the organic scaffold for mineralization