Because of its high prevalence in conjunction with obesity, diabetes, and insulin resistance, NAFLD has been increasingly appreciated as a hepatic manifestation of metabolic syndrome and is the leading cause of death from liver disease in the United States 1,2,3
The researchers analyzed the records to see how many patients developed one of four gastrointestinal conditions, and compared that rate to patients using another weight loss drug, bupropion-naltrexone
After 104 weeks on retatrutide, they lost an average of 85 pounds, or 30% of their body weight
Pharmacogenetic variation and metformin response
If there is clinical improvement and if a reticulocyte response is observed, the same amount may be given on alternate days for seven doses, then every 3 to 4 days for another 2 to 3 weeks