tirzepatide side effects mental health Can Mounjaro Cause Anxiety and Depression (July 2026 Update) Tirzepatide and Depression Risk |

But if you stay off the drug, expect cravings to return with full force

J Pharmacol Exp Ther 232(1):258262 Dalvi R, Dalvi P (1991) Comparison of the effects of piperine administered intragastrically and intraperitoneally on the liver and liver mixed-function oxidases in rats

The crossover design minimized individual variability, allowing each participant to serve as their control

As with many drugs used for weight loss, Mounjaros relatively newness means theres limited evidence on how long people need to take it or what they need to do to maintain weight loss after they stop

"Ozempic made my gums and teeth super-sensitive