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its to maintain balance and inhibit production if it becomes too high

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The REDEFINE 3 cardiovascular outcomes trial which will take several years to complete is not a prerequisite for initial market authorisation for obesity treatment, but its results will likely be important for subsequent label expansion and for establishing the cardiovascular benefit profile that has proven so valuable for tirzepatide and semaglutide

Moreover, evidence on the long-term efficacy and safety of prolonged use, as well as combination therapy with other drugs, remains insufficient