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Antibodies to Porphyromonas gingivalis are frequently elevated in patients with periodontitis and have been associated with increased risk of cardiovascular disease due to both microbial exposure and host immune response [42]
One large electronic database study showed there was a significantly increased risk of diabetic macular edema following GLP-1RA initiation compared to sodium-glucose cotransporter 2 inhibitors (SGLT2i)
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Some patients report improved leg pain, softer nodules, reduced tenderness in lipedema areas, and decreased knee pain
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