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It is a poorer fit, or warrants caution, in patients with known sulfur or sulfite sensitivity, in poorly controlled asthma, and in anyone whose expectations are anchored to unproven claims particularly cosmetic skin-lightening
The platform emphasizes transparency around sourcing and may appeal to patients seeking lower-cost or customized formulations without compromising safety or regulatory oversight
However, at the moment, Novo Nordisks orally formulated GLP-1 drug (Rybelsus TM semaglutide), which is on the market, has only achieved a six percent market share
however, this analysis is limited by a large proportion of data missingness (Supplementary Table S1).The pattern of association of GLP1-RA with decreased acute healthcare utilization, CKD progression and all-cause death despite no difference in CV outcomes persisted in additional analyses excluding patients with ESRD (Supplementary Table S2) and after adjusting for A1c at follow-up and use of other anti-hyperglycemic medications (Supplementary Table S3)
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