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Dosage adjustments often become necessary with oral forms to compensate for reduced bioavailability, which can introduce variability and complexity into research
Journal of Cellular Biochemistry Supplement (1996) 24:32-91 (HHS Ref
25 Patients diagnosed with vitamin B 12 deficiency whose history and physical examination do not suggest an obvious dietary or malabsorptive etiology should be tested for pernicious anemia with anti-intrinsic factor antibodies (positive predictive value = 95%), particularly if other autoimmune disorders are present
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