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Dosage should begin conservatively and adjust based on tolerance and clinical markers

Xu C, Sun L, Ren F, Huang P, Tian Z, Cui J, et al

Without adequate hydration, these bound compounds cannot be cleared from the body efficiently, limiting the supplement's full detoxification benefits

Green et al 26 Severe clinical abnormalities should be treated intensively with B 12 , cyanoB 12 or hydroxyB 12 : HydroxyB 12 is commonly used in Europe, often at intervals of 23 months, as it seems to have better retention than cyanoB 12

I dont know the answer to this, but I think right now, without having anybody being able to monitor this, I dont know how we get past just the influencer phase of people recommending this, because I dont know how were going to get there