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In the Phase 2 trial, participants showed reductions in liver fat content as measured by MRI-based proton density fat fraction (MRI-PDFF) assessments, with some individuals demonstrating marked reductions in hepatic steatosis
Current FDA labeling for the major GLP-1 RAs does not list a specific interaction with probiotics, and a direct enzyme-based interaction is not expected based on available data
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Clin Pharmacol Ther 55(6):681692
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